One trial found that a “game-changing” diabetes medication could help obese people lose up to 20% of their body weight.
A study of 2,539 overweight and obese participants without diabetes found that a weekly dose of tirzepatide can lead to significant weight loss when used in conjunction with diet and exercise.
The international research team divided the volunteers into four groups and, over 72 weeks, they received three different doses of tirzepatide or a placebo.
The group taking the highest dose, 15 mg, lost significant weight, according to the study published in the New England Journal of Medicine. 57% of them reduced 20% of their body weight.
Obesity experts told The Guardian that tirzepatide was a “game changer” but warned of side effects such as vomiting and diarrhea, and said weight could be regained when people stopped taking it. .
Dr. Anya Gastropov, from Yale University and lead author of the research, said: “We need to treat obesity like any chronic disease, through effective and safe approaches that address the underlying mechanisms of the disease. , and These findings prove that tirzepatide can do just that. ”
But Tom Sanders, emeritus professor of nutrition and dietetics at King’s College London, said there were also concerns about the drug’s effects on the pancreas.
He added, “This type of medication is only meant to provide participants with a low -calorie prescribed diet along with medication, so it’s not a magic bullet.”
Source: Daily Mail
Source: Arabic RT
